Which material was commonly used in the earliest dermal fillers?

Bovine collagen was one of the first materials used in dermal fillers due to its availability and biocompatibility with human tissue. Bovine collagen is derived from cows and was recognized for its ability to safely integrate into the human body, providing volume and reducing the appearance of wrinkles and fine lines.

Its use paved the way for advancements in the aesthetic industry, as it was relatively easy to source and could deliver satisfactory results in soft tissue augmentation. This early approach laid the foundation for later innovations in dermal fillers, as it demonstrated the potential of biological materials to enhance facial features safely.

While synthetic polymers, plant-based substances, and human tissue have since become more common as fillers, they were not the primary materials used in the initial development of dermal fillers. The use of bovine collagen marked a significant step in cosmetic dermatology, influencing subsequent research and the production of more advanced fillers.